An investigation published in The BMJ raises new concerns over the landmark clinical trial (PLATO) that was used to gain worldwide approval for the anti-platelet drug ticagrelor (Brilinta in the ...

Non-ST-segment elevation acute coronary syndrome; OPTIMUS-3: Optimizing Anti-Platelet Therapy in Diabetes Mellitus; PCI: Percutaneous coronary intervention; PRINCIPLE-TIMI: Prasugrel in Comparison ...

Platelets with FCεRI and FCεRII receptors ... rupture showing a novel way towards our effort to prevent acute coronary syndromes? Drugs, substances targeting the stem cell factor that is ...

Acute coronary syndromes are sudden episodes of reduced or no blood flow and therefore oxygen delivery to part of the heart, usually as a result of narrowing or blockage of an artery.

Antiplatelet therapy is standard in most cases of ST-segment elevation and non-ST-segment elevation (NSTE) acute coronary syndromes (ACS ... Study assessing anti-Platelet Effects of AZD6140 ...

But the FDA approved ticagrelor over these objections, sparking a long and rancorous dispute over PLATO. However, since the 2011 approval for acute coronary syndrome, a host of other studies have ...

A new study uncovers how the COVID-19 pandemic reshaped emergency care for acute coronary syndrome ... to gain worldwide approval for the anti-platelet drug ticagrelor (Brilinta in the US and ...

The acute coronary syndrome market is experiencing significant growth, driven by the increasing prevalence of both acute ...

The acute coronary syndromes include unstable angina ... resulting in decreased thromboxane A2 production and platelet inhibition. P2Y12 receptor blockers/inhibitors: These include clopidogrel ...

Background Coronary heart disease (CHD) remains a leading cause of mortality and disability worldwide. Approximately half of the patients who have had a prior hospital admission for CHD will have a ...

The acute coronary syndrome market is experiencing significant growth, driven by the increasing prevalence of both acute myocardial infarction (AMI) and unstable angina, an aging global population ...