Planar cell polarity (PCP) refers to the coordinated ... particularly focusing on the role of Wnt signaling pathways and mechanical forces in regulating cell behavior during embryonic development ...
An analysis of genetic sequencing data and gene and protein expression studies from patients with yellow nail syndrome (YNS) found that defects in the planar cell polarity (PCP) pathway play a ...
Our approach is to study two conserved mechanisms, the "core" Frizzled-dependent planar polarity pathway and the Fat/Dachsous pathway. Our goal is to dissect the feedback and cell-cell communication ...
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