Engineered T cells could help patients overcome resistance to CAR T cell therapy
Physician-researchers with City of Hope have developed a way to add features to T cells to help them overcome mechanisms of ...
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CAR-specific monoclonal FMC63 antibodies for CD19 CAR expression evaluation
In CAR-T therapy, CD19 is now the most extensively used target. It has been confirmed to be effective and safe for the treatment of CLL, B-ALL and B cell lymphoma. FMC63, an IgG2a mouse monoclonal ...
Drug screening platform identifies compound for reinvigorating exhausted CAR-T cells
A research team led by Prof. Wang Haoyi from the Institute of Zoology (IOZ) of the Chinese Academy of Sciences has developed ...
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Incyte/Morphosys take on CAR-Ts with $198,000 per year antibody
a protein on the surface of B-cells that is also targeted by Amgen’s bispecific antibody Blincyto (blinatumomab) for acute lymphoblastic leukaemia (ALL), as well as two CAR-T therapies ...