Study reveals critical role of tRNA modifying enzyme in brain function
A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation ...
Importance of RNA modifications in fungal infection resistance could lead to better treatments
An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic, claims a ...
Nature4d
RNA modification articles from across Nature Portfolio
RNA modifications are changes to the chemical ... and cryogenic electron microscopy to elucidate the mechanism of human tRNA 3′ processing. Their results show how mitochondria-specific subunits ...
SAMURI's intricate 3D structure offers insights into RNA modification
In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, ...
Helsinki3y
RNAcious laboratory
This is achieved by specialized tRNA modification enzymes acting alone or as part of complex pathways. These post-transcriptional modifications provide structural integrity to the tRNA molecule and ...
EurekAlert!20d
Adenosine-to-inosine RNA editing in cancer: Molecular mechanisms and downstream targets
Adenosine-to-inosine (A-to-I) RNA editing is a prevalent post-transcriptional modification that affects the structure and function of RNA molecules, including double-stranded RNA, tRNA ...
Science Daily27d
Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the ... "This was surprising, as no other human USP enzyme shows such preference for a specific linkage ...