The more than 2,300-mile Mississippi River invites travelers to discover its multifaceted heritage, with a vast range of deeply rooted culture, music and history. A cruise is a fantastic way to ...

American Cruise Lines' "Great United States" itinerary will depart from Portland, Oregon in May 2025, ending in Boston 51 ...

Contributors, John and Sandra Nowlan offer an insider’s look at their Mississippi River cruise on American Melody, one of ...

For an alternative type of break on the water, winding your way inland might sound similar but it’s a vastly different ...

American Cruise Lines unveiled its 2025 program, featuring eight new itineraries and a 51-day Great United States river ...

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The Mississippi River looms large in the American psyche. Long before trains, planes and automobiles, Native people — and later fur traders, rum runners, colonists and goods — traversed the ...

For history buffs, foodies, and music lovers alike, a cruise along the United States' own Mississippi River offers a bounty of opportunities to experience the rich culture of America's heartland.

Opt for American Cruise Lines’ seven-night Historic Mississippi River Cruise if you really want to immerse yourself in the Deep South. The roundtrip begins in New Orleans, where you can ...