Did it have a little adapter in the box ... It is unlikely then that you could take a modern USB-only device and an unholy chain of USB-to-PS/2-to-serial adapters, and have it work as a serial ...

Add or Remove Programs entry for FTDI USB Serial Converter Drivers. This is a driver pack that allows USB ports to be used to connect to Serial bus devices with a USB - Serial adapter cable.

the cheap USB to serial adapter board works perfectly, although anyone attempting to duplicate these efforts might want to look into replacing the USB mini port with a USB micro port.