The four colony-stimulating factors (CSFs) are glycoproteins that regulate the generation and some functions of infection-protective granulocytes and macrophages. Recombinant granulocyte-CSF (G ...

The eyes have long been regarded as "immune-privileged" organs. Immunological system of ocular tissues prevents or resolves ...

The team has focused on two proteins that are essential to the immune system: one is IFNalpha2a, which has powerful antiviral and anti-cancer effects, and the other is macrophage-CSF, which is ...

The presence of the CSF-1 receptor may identify both macrophages, as well as CSF-1-producing tumor cells. Identification of the CSF-1 receptor by immunohistochemistry in human breast tumors is ...

This CSF-1R agonist, NKTR-422, demonstrated inflammation resolution and tissue repair markers induction in tissue resident macrophages without induction of monocytosis and enhanced the efficacy of ...

Our lead program, molgramostim inhalation solution (molgramostim), is an inhaled granulocyte-macrophage colony-stimulating factor (GM-CSF) in Phase 3 development for autoimmune pulmonary alveolar ...

These TAMs are polarized toward the M2 phenotype by CSF-1 and CCL2 ... 2011 Expert Reviews Ltd. Cite this: Tumor-associated Macrophages in Breast Cancer as Potential Biomarkers for New Treatments ...