If they’re not absorbed, LDL particles can accumulate to harmful effect in artery walls. ApoB100 has evaded structural ...

The core of the lipoprotein, containing cholesterol ester and TG, is nonpolar and hydrophobic, and the outer layer of the lipoprotein particle (containing free cholesterol, phospholipid ...

The findings could lead to more tailored treatments for cardiovascular disease. Scientists at the Institutes of Health (NIH) ...

Until now scientists have been unable to visualize the structure of LDL, specifically what happens when it links up with its receptor, a protein known as LDLR. Typically, when LDL binds to LDLR ...

Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of apolipoprotein B100 ...

ApoB100 is a key protein in normal metabolism and in heart disease. Beginning before the protein’s synthesis is completed, it collects cholesterol and fats into particles that allow these ...

Until now, scientists have been unable to visualize the structure of LDL, specifically what happens when it links up with its receptor, a protein known as LDLR. Typically, when LDL binds to LDLR ...