The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

the helix structure is unwound special molecules break the weak hydrogen bonds between bases, which are holding the two strands together this process occurs at several locations on a DNA molecule ...

Direct sequencing-based assays have limited sensitivity, while assays based on PCR restriction fragment-length polymorphisms (RFLPs), pyrosequencing, PCR–ligase detection reaction, mutant ...