Staged reduction of the chromosome complement of human–mouse hybrid cells has made possible the identification of the chromosome bearing the human gene for thymidine kinase. Effects of human ...

In the years following Takahashi and Yamanaka's initial success in reprogramming mouse cells, multiple groups used the same strategy to generate human iPS cells, which resemble human ES cells by ...

Around 700 million years ago, the animal kingdom began to branch off from single-celled organisms. Now, scientists have uncovered molecular tools that could have assisted the leap — and ...

Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is ...

A Historic Experiment in Genetic Reprogramming Scientists have made a significant leap by reprogramming mouse stem cells using genes from choanoflagellates, ancient unicellular organisms believed ...

Since its discovery in the 1990s, "programmed cell death protein 1," or PD-1, has been regarded as a leading target in cancer treatments.

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new ...