Excessive production of IL-1β drives the recurrent episodes of fever and systemic inflammation in certain ... the importance of IL-1Ra in immune homeostasis, these studies also provide some ...
The integrated and proper functioning of each system is paramount to the health of the other. Chronic inflammation ... immune and metabolic systems need to colocalize to maintain metabolic ...
A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the ...
The intestinal immune system faces a number of unique challenges due ... amplifying damage and potentially lead to systemic infection or chronic inflammatory disease including inflammatory bowel ...