Excessive production of IL-1β drives the recurrent episodes of fever and systemic inflammation in certain ... the importance of IL-1Ra in immune homeostasis, these studies also provide some ...

A lack of exposure to environmental factors might contribute to an immune system that overreacts, potentially leading to systemic reactions such as those encountered in inflammatory diseases and ...

The vaginal innate immune system represents the first line of ... equilibrium and the contribution of each element to the final homeostasis. Various adverse obstetric and gynecologic conditions ...

But in those susceptible to periodontitis—due to genetics, behaviours like smoking and poor nutrition or a systemic vulnerability—the inflammation ... in our immune system and in our well ...

The intestinal immune system faces a number of unique challenges due ... amplifying damage and potentially lead to systemic infection or chronic inflammatory disease including inflammatory bowel ...