A mathematical model suggests that existing HPA-targeting drugs failed in clinical trials for mood disorders because the ...

Systemic absorption increased by broken or ... Discontinue or reduce frequency, dose, or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs.

What are the mechanisms of glucocorticoid negative feedback regulation of the HPA axis? The glucocorticoid stress hormones ... Utilizing the rat as an in vivo model, we use endocrine, pharmacological ...

This approach focuses on uncovering the impact of nervous and endocrine system functions and dysfunctions ... Increased activity of the HP axis, along with reduced feedback by endogenous ...