More information: Françoise Boismal et al, Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging, Aging (2024). DOI: 10. ...
The study showed that aging alters fibroblasts in ways that enable them to promote pancreatic cancer tumor growth. Older ...
Measuring mitochondrial respiration in frozen tissue samples provides the first comprehensive atlas of how aging affects mitochondrial function in mice.
More information: Casper Soendenbroe et al, Muscle fibroblasts and stem cells stimulate motor neurons in an age and exercise‐dependent manner, Aging Cell (2024). DOI: 10.1111/acel.14413 ...
This loss could include chronic injury or aging. The cells responsible for repair are mainly fibroblasts, and the molecular basis for their responses includes signaling through the cytokines TGF-β and ...