Both brands contain the same active ingredients: acetaminophen, aspirin, and caffeine. However, they are marketed to serve different purposes. Excedrin Migraine is meant to relieve pain associated ...

Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; coated caplets. Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma ...

Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; caplets. May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed ...

aspirin, and caffeine (Excedrin Extra Strength, Excedrin Migraine, and generics). If your migraines are moderate to severe in pain intensity, and/or disrupt your life, you might benefit from a ...