Enzymes are crucial to life. They are nature's little catalysts. In the gut, they help us digest food. They can enhance ...

Innovative therapies revive a once-undruggable mitochondrial aging regulator through a revolutionary enzyme activation ...

leading to an increase in enzyme activity. This means the active site loses its important shape and can no longer form enzyme-substrate complexes, leading to a decrease in enzyme activity.

This Review summarizes and unifies recent advancements, focusing on key enzymes that catalyze these modifications. Plant-specific class III glutaredoxins regulate the activity of TGA transcription ...

A groundbreaking discovery has unveiled a promising avenue in diabetes research. Scientists have identified a novel enzyme, SNO-CoA-assisted nitrosylase (SCAN), which plays a crucial role in ...

These phosphorylation reactions control the activity of many enzymes involved in intracellular signaling pathways. Specifically, the addition of phosphate groups causes a conformational change in ...

A new mouse study by researchers at the University of California (UC), San Diego, School of Medicine reveals that an enzyme called MICAL2 promotes tumor growth and spread in pancreatic ductal ...

Tumor cells lacking MICAL2 showed reduced KRAS activity, disrupting the ... This study redefines the role of enzymes like MICAL2 in cancer biology. By revealing how a regulatory protein can ...