Researchers at the University of Chicago have successfully captured detailed images of adhesion G protein-coupled receptors, ...
Using a method known as “rational drug design,” Elion and Hitchings were able to successfully interfere with cell growth, giving way to a number of effective drugs for treating leukemia, gout, malaria ...
A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...
These findings provide a fresh framework for understanding GPR6 function with a detailed basis for structure-based drug design, offering hope for improved future treatments of Parkinson's disease.
Traditional computer-aided drug design (CADD) helps researchers screen for potential new drug-like molecules and predict their biological activity before completing laboratory experiments.