The system is not limited to observing proteins ... Boulton applied the same approach to another important DNA repair protein, HELQ. His lab’s previous work showed which other molecules HELQ ...

DNA repair: A look inside the cell's 'repair café'. ScienceDaily . Retrieved December 10, 2024 from www.sciencedaily.com / releases / 2024 / 11 / 241121115648.htm ...

The findings also revealed that DNA can be repaired by cooperation between repair proteins. These proteins organize themselves into "hubs," where multiple damaged DNA regions come together. These ...

Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in prostate ...

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...

It uses synthetic oligonucleotides together with the cell's inherent DNA repair system to direct single base pair changes. Exon skipping technologies remain hindered by aberrant splicing and low ...

If DNA damage is not properly repaired, mutations can occur, which may result in diseases like cancer. Cells use repair systems to fix this damage, with specialized proteins locating and binding ...

RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

The researchers studied DNA recombination in bacteria, which are relatively easier to study than humans but share a very similar system for the repair of DNA breaks. The research focussed on the ...

The Shu complex, it turns out, may act as a backup system for BRCA2, a well-known protein that when mutated may lead to breast and endometrial/uterine cancer. SWSAP1-SWS1 helps repair broken DNA ...