DNA polymerase is responsible for the process of DNA replication, during which a double-stranded DNA molecule is copied into two identical DNA molecules. Scientists have taken advantage of the ...

Scientists have yet to identify a polymerase that can add bases to ... During circular DNA replication, the excised primer is readily replaced by nucleotides, leaving no gap in the newly ...

Free DNA nucleotides – needed to form the new strands. DNA polymerase – an enzyme that adds new nucleotides to a growing strand of DNA. Primers – A primer is a short strand of nucleotides th ...

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate copying of genetic information. DNA polymerase enzymes use the existing DNA strand as a template and ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...

Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...