Activator proteins bind to regulatory sites on DNA nearby to promoter regions that act as on/off switches. This binding facilitates RNA polymerase activity and transcription of nearby genes.

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say.

Recombinant antibody production involves the use of recombinant DNA technology ... appropriate sequence for binding, you may have to study the 3D structure of the proteins and then only choose ...

The Bioinformatics ... which DNA sequence changes can give rise to altered gene expression. To this end, investigating computational approaches to detect regulatory elements within genomic sequences ...