T-cell therapy yielded encouraging response rates and safety findings among patients with relapsed or refractory chronic ...

the T cell exhaustion issue has so far been one of the main obstacles in its wider use. With clinical trials of SUV39H1 knockout CAR T cells being a distinct possibility at this point, it could be ...

Because of inherent differences between hematologic and solid malignancies, researchers expected solid tumors to pose more ...

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor ...

Physician-researchers with City of Hope have developed a way to add features to T cells to help them overcome mechanisms of chimeric antigen receptor (CAR ... reduce T cell exhaustion, another ...

Dr. Sattva S. Neelapu discusses the intricacies of CAR T-cell therapy treatment and care for patients with hematologic ...

Chimeric antigen receptor (CAR) T cell therapy is an immunotherapy ... and music. Through treatment challenges, she remained resilient, embracing life with renewed purpose and joy. The Princess of ...

Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center identified a cocktail of three different drugs that can be used to generate more robust ...

Lyell is also developing next-generation CAR T-cell product candidates enhanced with anti-exhaustion and additional arming technologies, and manufactured with proprietary protocols. These approaches ...