Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). In the PNS, one Schwann cell forms a ...
Nave and his colleagues hypothesized that myelin, a protective fatty layer that encloses axons (i.e., nerve fibers) in the ...
Conditional knock-out mice in which Myrf is knocked out in the OL lineage cells completely fail to develop CNS myelin and exhibit severe neurological symptoms, eventually prematurely dying. Recently, ...
In CNS, the company is focused on disorders ... which is caused by gene duplication of peripheral myelin protein 22 (PMP22), and impacts Schwann cell survival and function.
The research report titled: “Selective retinoid X receptor agonism promotes functional recovery and myelin repair in ... develop IRX4204 for multiple nervous system indications.” ...
A long fibre (axon) which is insulated by a fatty (myelin) sheath ... These move towards the central nervous system (CNS). The CNS is the brain and spinal cord. It coordinates the responses.
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