orally bioavailable CXCR4 antagonist CXCR4 and CCR5 are the two major coreceptors for HIV-1 infection. Coreceptors are responsible for a crucial step between Env binding to the receptor CD4 and ...
Castor, Principal Investigator, "We are utilizing targeted nanoparticles manufactured by our proprietary PNS (polymer nanoparticles) technology to transport the anti- CCR5 antagonist across the ...
HIV-1 entry into cells is an attractive target for new antiviral agents. But will inhibitors aimed at the CCR5 co-receptor force HIV-1 to evolve more virulent forms? Other targets for entry ...
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