In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research ...

A Norovirus protein and RNA undergo liquid-liquid phase separation to form “replication factories” inside a host cell ...

Scientists have discovered how human norovirus creates special compartments inside cells to help it multiply and spread.

New method reveals the nature of biomolecular condensates through in vivo targeting and manipulation In schoolbooks, animal cells are usually depicted as a membrane bubble full of smaller compartments ...

Instead, they are biomolecular condensates, structures resembling a bubble formed by liquid-liquid phase separation. These ...

Combining bioinformatics and experimetal approaches, researchers have discovered replication hubs for human norovirus, the leading cause of viral gastroenteritis accounting for an estimated 685 ...

Research on norovirus replication hubs reveals RNA polymerase's key role in viral replication, offering potential antiviral ...

Dewpoint, founded in 2018, focuses on the application of biomolecular condensate biology towards the development of a new generation of therapeutics to address diseases of high unmet need. Condensates ...

TDP-43 abnormally accumulates in membrane-less cytoplasmic structures, known as biomolecular condensates, leading to neuronal dysfunction in ALS patients. Using their high-content, high-throughput ...

Racki had been studying these structures in bacterial cells, while Deniz's next-door lab was exploring the physical chemistry of biomolecular condensates for the past decade. Collaboration ...

Combining bioinformatics and experimetal approaches, researchers have discovered replication hubs for human norovirus, the leading cause of viral gastroenteritis accounting for an estimated 685 ...