set the scene for what followed on the role of apoptosis in cancer biology. The discovery of the Bcl-2 protein family, as well as p53 and its involvement in regulating apoptosis, and the CD95 ...
A new study describes a molecular mechanism that could drive the design of strategies to eliminate senescent cells in cancer ...
After treating a tumour with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do not divide, are involved in the ageing process and are resistant to cell ...
After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear. These are cells that do ...
BCL-2 inhibitors, such as venetoclax (Venclexta) work by targeting the BCL-2 protein, which plays a key role in preventing apoptosis, or programmed cell death. According to John Seymour, MD, ...