In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

Our findings demonstrate that mitochondria dynamics do not regulate apoptosis activation in C. elegans and reveal distinct roles for drp-1 and fis-2 as mediators of cell-death execution downstream of ...

Activation of these trigger proteins disintegrates the mitochondria, and instantly sets off a series of caspase enzymes that help initiate apoptosis (cell death). "Our study shows how cancer cells ...

Glaucoma is a progressive eye disorder characterized by fluid buildup inside the eye, causing ocular hypertension. By 2040, ...

Recent research indicates that intermittent fasting could slow hair growth by causing oxidative stress and apoptosis in hair follicle stem cells. Mice studies and a small human trial show reduced hair ...

Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...

Malignant tumors remain a serious threat to human health and life and are a major public health problem globally. Herein, we ...

Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth-;at least in mice.

Activation of these trigger proteins disintegrates the mitochondria, and instantly sets off a series of caspase enzymes that help initiate apoptosis (cell death). Our study shows how cancer cells ...

leading to apoptosis, a programmed cell death process, and, consequently, a reduction in melanoma cell growth. Further research is necessary to fully understand its potential in treating advanced ...

Multiple myeloma cells carry a protein called BCL-2 that keeps the cell from triggering apoptosis. Venclexta inhibits BCL-2, restoring natural cell death for these cancer cells. The U.S. Food and Drug ...