[23] Alfuzosin undergoes extensive hepatic metabolism; however, its metabolism is not saturable. Only 11% of each dose is excreted by the kidneys as unchanged drug; 75-91% of alfuzosin metabolites ...

The extended-release (ER) formulations of alfuzosin for once- or twice-daily administration are associated with small variations in peak and trough serum drug levels, which may contribute to the ...