[23] Alfuzosin undergoes extensive hepatic metabolism; however, its metabolism is not saturable. Only 11% of each dose is excreted by the kidneys as unchanged drug; 75-91% of alfuzosin metabolites ...

[17,18] Tamsulosin has a low affinity for vascular α 1-receptors, which explains why hypotension is an uncommon adverse effect of tamsulosin therapy and why the drug has not been studied for use ...