This pathway, called the “PI3K/AKT pathway,” can be activated by drugs that aim to block HER2, and it can provide a way to rescue the cancer cells. Research conducted by Shagisultanova has ...

The company’s head of oncology, Dave Fredrickson, said the approval of Truqap “reinforces the important role of the PI3K/AKT pathway in HR-positive breast cancer and the critical need to test ...

Researchers identified nicotinamide (NAM) and pyridoxine (PN) as safe, synergistic nutrients that restore muscle stem cell ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...