Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosysnthesis, CYP17, and blocks the ...

Giles Turner, from Sussex, is paying for abiraterone privately at a cost of £250 per month Thousands of patients in England and Northern Ireland are missing out on a life-extending prostate ...

However, the addition of a GnRH agonist to abiraterone acetate resulted in a ... study in 33 patients with progressive CRPC at 250, 500, 750 and 1000 mg daily. [46] A total of 18 out of 33 ...