Colonisation of the Americas at the end of the 15th Century killed so many people, it disturbed Earth's climate. That's the conclusion of scientists from University College London, UK. The team ...

The history of syphilis has long been debated, with experts unable to come to a consensus over the origins of the outbreak that rocked Europe in the 16th century.

And Portuguese traders had been taking slaves to their colonies since the 15th Century. The US Congress has established a special commission to mark 400 years of African-American history this year.

"Their introduction to Europe starting in the late 15th century is most consistent with ... "While indigenous American groups harboured early forms of these diseases, Europeans were instrumental ...