Holcomb is a city in Finney County, Kansas, United States. As of the 2020 census, the population of the city was 2,245. It is located south of Highway 50. Holcomb took its name from a local hog farmer. The city was a station and shipping point on the Atchison, Topeka and Santa Fe Railway. The first post office in Holcomb was established in December 1909.