Quepos is a district of the canton of Quepos, in the province of Puntarenas, Costa Rica. The town is named for the native Quepo Indians who inhabited the place in the colonial era. The area was home to the native Quepoa people of this specific Costa Rican region. In 1563, Spanish Catholic conquistadores, led by Juan Vázquez de Coronado…Quepos is a district of the canton of Quepos, in the province of Puntarenas, Costa Rica. The town is named for the native Quepo Indians who inhabited the place in the colonial era. The area was home to the native Quepoa people of this specific Costa Rican region. In 1563, Spanish Catholic conquistadores, led by Juan Vázquez de Coronado, settled the area and founded the settlement of San Bernardino de Quepo. The local native Quepo people were then subsequently subjugated by Juan Vázquez and his conquistadores.