El Puerto de Santa María, locally known as El Puerto and historically in English as Port Saint Mary, is a municipality of Spain located on the …El Puerto de Santa María, locally known as El Puerto and historically in English as Port Saint Mary, is a municipality of Spain located on the banks of the Guadalete River in the province of Cádiz, Andalusia. As of 2016, the city has a population of c. 88,184, of which some 50,000 live in the urban center, and the remainder in the surrounding areas.