Monroe County is a county located in the southwestern part of the U.S. state of Alabama. As of the 2020 census, the population was 19,772. Its county seat is Monroeville. Its name is in honor of James Monroe, fifth President of the United States. It is a dry county, in which the sale of alcoholic beverages is restricted or prohibited, but Frisco City and Mo…Monroe County is a county located in the southwestern part of the U.S. state of Alabama. As of the 2020 census, the population was 19,772. Its county seat is Monroeville. Its name is in honor of James Monroe, fifth President of the United States. It is a dry county, in which the sale of alcoholic beverages is restricted or prohibited, but Frisco City and Monroeville are wet cities.