Keowee was a Cherokee town in the far northwest corner of present-day South Carolina. It was the principal town of what were called the seven Lower Towns, located along the Keowee River. Keowee was situated on the Lower Cherokee Traders' Path, part of the Upper Road through the Piedmont. In 1752 the Cherokee established New Keowee Town nea…Keowee was a Cherokee town in the far northwest corner of present-day South Carolina. It was the principal town of what were called the seven Lower Towns, located along the Keowee River. Keowee was situated on the Lower Cherokee Traders' Path, part of the Upper Road through the Piedmont. In 1752 the Cherokee established New Keowee Town nearby, off the traders' path but in a more defensible location.
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