Camagüey is a city and municipality in central Cuba and is the nation's third-largest city with more than 333,000 inhabitants. It is the capital o…Camagüey is a city and municipality in central Cuba and is the nation's third-largest city with more than 333,000 inhabitants. It is the capital of the Camagüey Province. It was founded as Santa María del Puerto del Príncipe in 1514, by Spanish colonists on the northern coast and moved inland in 1528, to the site of a Taino village named Camagüey. It was one of the seven original settlements founded in Cuba by the Spanish. After Henry Morgan burned the city in the 17th century, it was redesigned like a maze so attackers would find it hard to move around inside the city.